2018年3月23日星期五

The chemerin receptor CMKLR1 is a functional receptor for amyloid-β peptide

The chemerin receptor CMKLR1 is a functional receptor for amyloid-β peptide

L Peng, Y YuJ Liu, S Li, H He… - Journal of Alzheimer's …, 2015 - content.iospress.com
Abstract Amyloid-β peptides such as Aβ 1-42 (Aβ 42) play a pivotal role in the progression of
Alzheimer's disease (AD). Aβ 42 is neurotoxic and can activate microglial cells. These cells
in turn migrate toward senile (neuritic) plaques and help to clear Aβ deposits through an …


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