2018年6月28日星期四

[HTML] The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch

[HTML] The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch

AA Celik, T Kraemer, T Huyton, R Blasczyk… - Immunogenetics, 2016 - Springer
Human leukocyte antigen (HLA)-E molecules are potent inhibitors of NK cell-mediated
killing. Low in polymorphisms, two alleles are widely expressed among diverse populations:
HLA-E* 01: 01 and HLA-E* 01: 03. Both alleles are distinguished by one SNP resulting in …


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