2018年6月28日星期四

(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains

(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains

S Garcia-Ratés, P Morrill, H Tu, G Pottiez, AS Badin… - …, 2016 - Elsevier
The primary cause of Alzheimer's disease is unlikely to be the much studied markers
amyloid beta or tau. Their widespread distribution throughout the brain does not account for
the specific identity and deep subcortical location of the primarily vulnerable neurons …


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