2018年6月28日星期四

[HTML] Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide

[HTML] Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide

S Liu, J Desharnais, PV Sahasrabudhe, P Jin, W Li… - Scientific reports, 2016 - nature.com
IL-17A is a pro-inflammatory cytokine that has been implicated in autoimmune and
inflammatory diseases. Monoclonal antibodies inhibiting IL-17A signaling have
demonstrated remarkable efficacy, but an oral therapy is still lacking. A high affinity IL-17A …


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