2018年7月25日星期三

Affinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential

Affinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential

Q ZhaoM Ahmed, DV Tassev, A Hasan, TY Kuo… - Leukemia, 2015 - nature.com
Abstract WT1 126 (RMFPNAPYL) is a human leukocyte antigen-A2 (HLA-A2)-restricted
peptide derived from Wilms tumor protein 1 (WT1), which is widely expressed in a broad
spectrum of leukemias, lymphomas and solid tumors. A novel T-cell-receptor (TCR)-like …


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