2018年7月25日星期三

Defective natriuretic peptide receptor signaling in skeletal muscle links obesity to type 2 diabetes

Defective natriuretic peptide receptor signaling in skeletal muscle links obesity to type 2 diabetes

M Coué, PM Badin, IK Vila, C Laurens, K Louche… - Diabetes, 2015 - Am Diabetes Assoc
Circulating natriuretic peptide (NP) levels are reduced in obesity and predict the risk of type
2 diabetes (T2D). Since skeletal muscle was recently shown as a key target tissue of NP, we
aimed to investigate muscle NP receptor (NPR) expression in the context of obesity and …


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