2018年7月1日星期日

α‐Peptide–Oligourea Chimeras: Stabilization of Short α‐Helices by Non‐Peptide Helical Foldamers

α‐Peptide–Oligourea Chimeras: Stabilization of Short α‐Helices by Non‐Peptide Helical Foldamers

J Fremaux, L Mauran, K Pulka‐Ziach… - Angewandte Chemie …, 2015 - Wiley Online Library
Short α‐peptides with less than 10 residues generally display a low propensity to nucleate
stable helical conformations. While various strategies to stabilize peptide helices have been
previously reported, the ability of non‐peptide helical foldamers to stabilize α‐helices when …


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