Silibinin inhibits acetylcholinesterase activity and amyloid β peptide aggregation: a dual-target drug for the treatment of Alzheimer's disease

Silibinin inhibits acetylcholinesterase activity and amyloid β peptide aggregation: a dual-target drug for the treatment of Alzheimer's disease

S Duan, X Guan, R Lin, X Liu, Y Yan, R Lin, T Zhang… - Neurobiology of …, 2015 - Elsevier

Alzheimer's disease (AD) is characterized by amyloid β (Aβ) peptide aggregation and
cholinergic neurodegeneration. Therefore, in this paper, we examined silibinin, a flavonoid
extracted from Silybum marianum, to determine its potential as a dual inhibitor of …

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