The non‐peptide GLP‐1 receptor agonist WB4‐24 blocks inflammatory nociception by stimulating β‐endorphin release from spinal microglia

The non‐peptide GLP‐1 receptor agonist WB4‐24 blocks inflammatory nociception by stimulating β‐endorphin release from spinal microglia

H Fan, N Gong, TF Li, AN Ma, XY Wu… - British journal of …, 2015 - Wiley Online Library

Background and Purpose Two peptide agonists of the glucagon‐like peptide‐1 (GLP‐1)
receptor, exenatide and GLP‐1 itself, exert anti‐hypersensitive effects in neuropathic, cancer
and diabetic pain. In this study, we have assessed the anti‐allodynic and anti‐hyperalgesic …

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