Wnt-β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cells

Wnt-β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cells

Z Saidak, C Le Henaff, S Azzi, C Marty… - Journal of Biological …, 2015 - ASBMB

Results: CRRETAWAC-mediated α5β1 integrin priming promotes osteoblast differentiation
via PI3K-Wnt-β-catenin signaling independently of RGD-like REET sequence. Systemic
delivery of α5β1 priming peptide improved long bone microarchitecture in senescent …

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