2018年3月1日星期四

[HTML] Characterizing apolipoprotein E ε4 carriers and noncarriers with the clinical diagnosis of mild to moderate Alzheimer dementia and minimal β-amyloid peptide …

[HTML] Characterizing apolipoprotein E ε4 carriers and noncarriers with the clinical diagnosis of mild to moderate Alzheimer dementia and minimal β-amyloid peptide …

SE Monsell, WA Kukull, AE Roher, CL Maarouf… - JAMA …, 2015 - jamanetwork.com
Importance β-Amyloid peptide (Aβ) plaques are a cardinal neuropathologic feature of
Alzheimer disease (AD), yet more than one-third of apolipoprotein E ε4 (APOE4) noncarriers
with the clinical diagnosis of mild to moderate Alzheimer dementia may not meet positron


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