[HTML] Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells

[HTML] Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells

K Lee, P Yu, N Lingampalli, HJ Kim… - International journal …, 2015 - ncbi.nlm.nih.gov

Abstract The treatment of myocardial infarction is a major challenge in medicine due to the
inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac
fibroblasts into functional cardiomyocytes via the delivery of transcription factor mRNAs has …

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