Potent and specific peptide inhibitors of human pro-survival protein Bcl-xL
S Dutta, J Ryan, TS Chen, C Kougentakis… - Journal of molecular …, 2015 - Elsevier
Abstract The Bcl-2 family of proteins plays a critical role regulating apoptosis, and pro-
survival Bcl-2 family members are important therapeutic targets due to their overexpression
in different cancers. Pro-apoptotic Bcl-2 homology 3 (BH3)-only proteins antagonize pro …
survival Bcl-2 family members are important therapeutic targets due to their overexpression
in different cancers. Pro-apoptotic Bcl-2 homology 3 (BH3)-only proteins antagonize pro …
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