Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1

Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1

K Grabowska, AK Puszko, PFJ Lipiński… - Bioorganic & medicinal …, 2016 - Elsevier

Abstract Neuropilin-1 (NRP-1) is a co-receptor of VEGFR (vascular endothelial growth factor
receptor), but it is also suggested that NRP-1 in tumour cells may serve as a separate
receptor for VEGF 165. Therefore molecules interfering with VEGF 165 binding to NRP-1 …

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