2018年6月1日星期五

Pharmacodynamics in Alzheimer's disease model rats of a bifunctional peptide with the potential to accelerate the degradation and reduce the toxicity of amyloid β-Cu …

Pharmacodynamics in Alzheimer's disease model rats of a bifunctional peptide with the potential to accelerate the degradation and reduce the toxicity of amyloid β-Cu …

D Wang, Q Zhang, X Hu, W Wang, X Zhu, Z Yuan - Acta biomaterialia, 2018 - Elsevier
The accumulation of the extracellular β-amyloid (Aβ) aggregates with metal ions in
conjunction with reactive oxygen species (ROS) is closely related to the pathogenesis of
Alzheimer's disease (AD). Accounting on Cu ions chelating of our previously designed …


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