2018年7月26日星期四

Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice

Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice

W Li, H Liu, M Yu, X ZhangM Zhang, JX Wilson… - The Journal of nutritional …, 2015 - Elsevier
Alzheimer's disease (AD) is associated with malnutrition, altered one-carbon metabolism
and increased hippocampal amyloid-β peptide (Aβ) accumulation. Aberrant DNA
methylation may be an epigenetic mechanism that underlies AD pathogenesis. We …


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