2018年7月25日星期三

[HTML] Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction

[HTML] Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction

AY Robin, KK Kumar, D Westphal, AZ Wardak… - Cell death & …, 2015 - nature.com
The BH3-only protein Bim is a potent direct activator of the proapoptotic effector protein Bax,
but the structural basis for its activity has remained poorly defined. Here we describe the
crystal structure of the BimBH3 peptide bound to BaxΔC26 and structure-based …


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