Structure diversification of vancomycin through peptide-catalyzed, site-selective lipidation: a catalysis-based approach to combat glycopeptide-resistant pathogens
S Yoganathan, SJ Miller - Journal of medicinal chemistry, 2015 - ACS Publications
The emergence of antibiotic-resistant infections highlights the need for novel antibiotic
leads, perhaps with a broader spectrum of activity. Herein, we disclose a semisynthetic,
catalytic approach for structure diversification of vancomycin. We have identified three …
leads, perhaps with a broader spectrum of activity. Herein, we disclose a semisynthetic,
catalytic approach for structure diversification of vancomycin. We have identified three …
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